Multifunctional serotonin agonist/antagonist (HSDD)
Who should not take Flibanserin
A contraindication is a condition under which Flibanserin (Flibanserin) should not be taken because the risk outweighs the benefit. Flibanserin has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 100mg dosing range.
Absolute contraindications
According to the prescribing information for Flibanserin, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Flibanserin can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Flibanserin acts as a serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist, with additional effects on dopamine and norepinephrine signalling.
Frequently asked questions
Can someone with heart disease take Flibanserin? ▾
Some forms of heart disease are absolute contraindications for Flibanserin, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Flibanserin use under specialist supervision. The prescribing information for Flibanserin should be reviewed.
Is Flibanserin safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Flibanserin at adjusted lower 100mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
Products containing Flibanserin
More on Flibanserin
- With alcoholFlibanserin and alcohol — is it safe to drink?
- With foodShould Flibanserin be taken with food?
- Side effectsFlibanserin side effects: common, rare and warning signs
- Dosage guideFlibanserin dosage guide: how much to take and when
- OnsetHow fast does Flibanserin start working?
- DurationHow long does Flibanserin last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.