5-alpha-reductase inhibitor (type II)
Who should not take Finasteride
A contraindication is a condition under which Finasteride (Finasteride) should not be taken because the risk outweighs the benefit. Finasteride has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 1mg dosing range.
Absolute contraindications
According to the prescribing information for Finasteride, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Finasteride can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Finasteride binds with high affinity to 5-alpha-reductase type II, blocking the conversion of testosterone into DHT.
Frequently asked questions
Can someone with heart disease take Finasteride? ▾
Some forms of heart disease are absolute contraindications for Finasteride, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Finasteride use under specialist supervision. The prescribing information for Finasteride should be reviewed.
Is Finasteride safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Finasteride at adjusted lower 1mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
Products containing Finasteride
More on Finasteride
- With alcoholFinasteride and alcohol — is it safe to drink?
- With foodShould Finasteride be taken with food?
- Side effectsFinasteride side effects: common, rare and warning signs
- Dosage guideFinasteride dosage guide: how much to take and when
- OnsetHow fast does Finasteride start working?
- DurationHow long does Finasteride last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.