Selective serotonin reuptake inhibitor (SSRI)
Escitalopram and changes in taste or smell
Changes in taste (dysgeusia) or smell (parosmia, anosmia) are an under-recognised side effect category. Some medications produce a metallic taste, a dulling of flavours, or unusual smell perception. Whether Escitalopram (Escitalopram) at 5mg, 10mg, 20mg causes these changes depends on Escitalopram; the experience is usually benign but can affect appetite and quality of life.
Why taste and smell change on Escitalopram
Taste and smell perception relies on receptors in the tongue and nose that are sensitive to systemic medications. Escitalopram can affect taste through several mechanisms: alteration of saliva composition, direct receptor interference, secretion in saliva of medication metabolites, or changes in zinc handling. Escitalopram selectively inhibits the serotonin reuptake transporter (SERT) at the synaptic cleft, increasing serotonin availability for postsynaptic receptors.
When changes need attention
Mild metallic taste or dulled flavours in the first weeks of Escitalopram at 5mg, 10mg, 20mg are common and often resolve as the body adjusts. Persistent severe loss of taste or smell, sudden onset, or interference with eating warrants prescriber review — both because the medication may need adjustment and because other causes (zinc deficiency, sinus disease) should be excluded.
Frequently asked questions
Can Escitalopram change my taste or smell? ▾
Yes, some users report taste or smell changes on Escitalopram at 5mg, 10mg, 20mg — typically a metallic or dulled-flavour sensation that develops in the first weeks. The prescribing information for Escitalopram lists frequency in clinical trials. Most cases are mild and resolve.
Will my taste come back when I stop Escitalopram? ▾
For most users, taste changes attributable to Escitalopram resolve within weeks of stopping the medication. Persistent loss after stopping, or severe loss while on therapy, deserves a clinical evaluation since other causes may be involved.
Products containing Escitalopram
More on Escitalopram
- With alcoholEscitalopram and alcohol — is it safe to drink?
- With foodShould Escitalopram be taken with food?
- Side effectsEscitalopram side effects: common, rare and warning signs
- Dosage guideEscitalopram dosage guide: how much to take and when
- OnsetHow fast does Escitalopram start working?
- DurationHow long does Escitalopram last?
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