Serotonin-norepinephrine reuptake inhibitor (SNRI)
What to do if you miss a dose of Duloxetine
Missing a dose of Duloxetine (Duloxetine) is common — most people will skip a dose at some point during a course. The right action depends on how long since the missed dose and whether Duloxetine is taken event-driven or daily at 20mg, 30mg, 60mg. The wrong action — doubling up — is not recommended.
For daily Duloxetine
If Duloxetine is taken daily for a chronic condition, take the missed dose as soon as you remember, unless it is almost time for the next scheduled dose. In that case skip the missed dose and continue normally. According to the prescribing information for Duloxetine, two doses should never be taken close together to "make up" for a miss.
For event-driven Duloxetine
If Duloxetine is used as needed (not on a fixed schedule), there is no "missed dose" in the conventional sense — simply take the planned dose when needed and observe the recommended gap before re-dosing. Duloxetine inhibits the reuptake of both serotonin and norepinephrine at the synapse, with weaker effect on dopamine.
Frequently asked questions
Should I double the dose if I missed Duloxetine? ▾
No. Doubling doses of Duloxetine to compensate is not recommended at any 20mg, 30mg, 60mg strength and increases the risk of side effects without improving efficacy. Take the next scheduled dose normally.
How many missed doses are too many? ▾
Occasional missed doses of Duloxetine are usually inconsequential. Repeated missed doses can compromise the therapeutic effect — for chronic conditions like those treated with Serotonin-norepinephrine reuptake inhibitor (SNRI), consistent dosing matters. If adherence is hard, discuss reminders, simpler schedules or alternative formulations with the prescriber.
Products containing Duloxetine
More on Duloxetine
- With alcoholDuloxetine and alcohol — is it safe to drink?
- With foodShould Duloxetine be taken with food?
- Side effectsDuloxetine side effects: common, rare and warning signs
- Dosage guideDuloxetine dosage guide: how much to take and when
- OnsetHow fast does Duloxetine start working?
- DurationHow long does Duloxetine last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.