GLP-1 receptor agonist
Who should not take Dulaglutide
A contraindication is a condition under which Dulaglutide (Dulaglutide) should not be taken because the risk outweighs the benefit. Dulaglutide has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 0.75mg, 1.5mg, 3mg, 4.5mg dosing range.
Absolute contraindications
According to the prescribing information for Dulaglutide, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Dulaglutide can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Dulaglutide activates the GLP-1 receptor in pancreatic beta cells, stimulating glucose-dependent insulin secretion and suppressing inappropriate glucagon release from alpha cells.
Frequently asked questions
Can someone with heart disease take Dulaglutide? ▾
Some forms of heart disease are absolute contraindications for Dulaglutide, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Dulaglutide use under specialist supervision. The prescribing information for Dulaglutide should be reviewed.
Is Dulaglutide safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Dulaglutide at adjusted lower 0.75mg, 1.5mg, 3mg, 4.5mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
Products containing Dulaglutide
More on Dulaglutide
- With alcoholDulaglutide and alcohol — is it safe to drink?
- With foodShould Dulaglutide be taken with food?
- Side effectsDulaglutide side effects: common, rare and warning signs
- Dosage guideDulaglutide dosage guide: how much to take and when
- OnsetHow fast does Dulaglutide start working?
- DurationHow long does Dulaglutide last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.