Progestogen with anti-mineralocorticoid and anti-androgen activity
Who should not take Drospirenone
A contraindication is a condition under which Drospirenone (Drospirenone) should not be taken because the risk outweighs the benefit. Drospirenone has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 3mg / 0.03mg, 3mg/0.02mg dosing range.
Absolute contraindications
According to the prescribing information for Drospirenone, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Drospirenone can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Drospirenone activates progesterone receptors to suppress ovulation and produce the contraceptive effect when combined with an estrogen.
Frequently asked questions
Can someone with heart disease take Drospirenone? ▾
Some forms of heart disease are absolute contraindications for Drospirenone, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Drospirenone use under specialist supervision. The prescribing information for Drospirenone should be reviewed.
Is Drospirenone safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Drospirenone at adjusted lower 3mg / 0.03mg, 3mg/0.02mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
Products containing Drospirenone
More on Drospirenone
- With alcoholDrospirenone and alcohol — is it safe to drink?
- With foodShould Drospirenone be taken with food?
- Side effectsDrospirenone side effects: common, rare and warning signs
- Dosage guideDrospirenone dosage guide: how much to take and when
- OnsetHow fast does Drospirenone start working?
- DurationHow long does Drospirenone last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.