Selective serotonin reuptake inhibitor (SSRI)
Citalopram and changes in taste or smell
Changes in taste (dysgeusia) or smell (parosmia, anosmia) are an under-recognised side effect category. Some medications produce a metallic taste, a dulling of flavours, or unusual smell perception. Whether Citalopram (Citalopram) at 10mg, 20mg, 40mg causes these changes depends on Citalopram; the experience is usually benign but can affect appetite and quality of life.
Why taste and smell change on Citalopram
Taste and smell perception relies on receptors in the tongue and nose that are sensitive to systemic medications. Citalopram can affect taste through several mechanisms: alteration of saliva composition, direct receptor interference, secretion in saliva of medication metabolites, or changes in zinc handling. Citalopram selectively inhibits the serotonin reuptake transporter, increasing synaptic serotonin availability with limited affinity for noradrenaline transporters or other receptors.
When changes need attention
Mild metallic taste or dulled flavours in the first weeks of Citalopram at 10mg, 20mg, 40mg are common and often resolve as the body adjusts. Persistent severe loss of taste or smell, sudden onset, or interference with eating warrants prescriber review — both because the medication may need adjustment and because other causes (zinc deficiency, sinus disease) should be excluded.
Frequently asked questions
Can Citalopram change my taste or smell? ▾
Yes, some users report taste or smell changes on Citalopram at 10mg, 20mg, 40mg — typically a metallic or dulled-flavour sensation that develops in the first weeks. The prescribing information for Citalopram lists frequency in clinical trials. Most cases are mild and resolve.
Will my taste come back when I stop Citalopram? ▾
For most users, taste changes attributable to Citalopram resolve within weeks of stopping the medication. Persistent loss after stopping, or severe loss while on therapy, deserves a clinical evaluation since other causes may be involved.
Products containing Citalopram
More on Citalopram
- With alcoholCitalopram and alcohol — is it safe to drink?
- With foodShould Citalopram be taken with food?
- Side effectsCitalopram side effects: common, rare and warning signs
- Dosage guideCitalopram dosage guide: how much to take and when
- OnsetHow fast does Citalopram start working?
- DurationHow long does Citalopram last?
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