Norepinephrine-dopamine reuptake inhibitor (NDRI) antidepressant
What to do if Bupropion is in shortage
Drug shortages happen periodically — manufacturing issues, supply chain disruptions, regulatory holds — and Bupropion (Bupropion) may become temporarily unavailable in some pharmacies or countries. For chronic users at 75mg, 100mg, 150mg, 300mg, knowing how to handle a shortage prevents unnecessary treatment interruption.
How shortages work for Bupropion
When Bupropion is in shortage, the pharmacist usually has several options: dispense an authorised generic of Bupropion, source from a different manufacturer of the same active ingredient, suggest a different formulation (e.g. liquid, dispersible) or, in extended shortages, ask the prescriber to consider an alternative Norepinephrine-dopamine reuptake inhibitor (NDRI) antidepressant agent. Bupropion inhibits the reuptake of norepinephrine and dopamine, with much weaker effect on serotonin reuptake.
Practical steps
According to general pharmacy practice, the first step in a Bupropion shortage is to ask the pharmacist about authorised generic availability — most shortages affect a single brand or strength, not the entire supply of Bupropion at 75mg, 100mg, 150mg, 300mg. The prescriber should be informed if the pharmacist needs to substitute or change formulation. Stockpiling or buying extra outside regulated channels is not the right response.
Frequently asked questions
What do I do if my pharmacy doesn't have Bupropion? ▾
Ask the pharmacist whether an authorised generic of Bupropion is available — usually yes — or whether another pharmacy in the area has stock of Bupropion at 75mg, 100mg, 150mg, 300mg. The pharmacist can also contact the prescriber if a formulation switch is needed.
Will Bupropion come back in stock? ▾
Most shortages are resolved within weeks to months as manufacturing or supply issues are fixed. Until then, the authorised generic of Bupropion is the standard alternative and is clinically equivalent to Bupropion at the same 75mg, 100mg, 150mg, 300mg strength.
Products containing Bupropion
More on Bupropion
- With alcoholBupropion and alcohol — is it safe to drink?
- With foodShould Bupropion be taken with food?
- Side effectsBupropion side effects: common, rare and warning signs
- Dosage guideBupropion dosage guide: how much to take and when
- OnsetHow fast does Bupropion start working?
- DurationHow long does Bupropion last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.