Norepinephrine-dopamine reuptake inhibitor (NDRI) antidepressant
How Bupropion affects libido and sex drive
Libido and sex drive are commonly affected by medications, sometimes intentionally (e.g. ED therapies) and sometimes as an unwelcome side effect. Bupropion (Bupropion) may or may not affect libido depending on Bupropion; this page outlines what is documented at 75mg, 100mg, 150mg, 300mg and what users typically report.
Documented effects of Bupropion on libido
Some medications in Norepinephrine-dopamine reuptake inhibitor (NDRI) antidepressant are designed specifically to affect sexual function; for those, libido changes are expected and central to the indication. Others have libido changes as side effects of altered hormones, mood, energy or autonomic function. According to the prescribing information for Bupropion, the documented frequency varies and is listed in the side-effect profile.
Managing libido changes
For unwanted libido suppression, the right response often depends on whether the issue is the medication itself, the underlying condition, fatigue, or relationship factors. Bupropion inhibits the reuptake of norepinephrine and dopamine, with much weaker effect on serotonin reuptake. A dose review, a switch within the same class, or addressing other contributors are all reasonable strategies and should be discussed with the prescriber rather than self-managed by stopping Bupropion at 75mg, 100mg, 150mg, 300mg.
Frequently asked questions
Does Bupropion lower libido? ▾
Some users on Bupropion report reduced libido, some report no change, and a few — particularly on indications targeting sexual function — report improvement. Whether this happens depends on Bupropion and individual factors. The prescriber can review options if libido changes are persistent or distressing.
Can libido recover after stopping Bupropion? ▾
For most users, libido changes attributable to Bupropion resolve within weeks of stopping the medication, though the timeline varies by active ingredient and individual. Persistent changes after stopping warrant medical evaluation, as the underlying condition may be the contributing factor.
Products containing Bupropion
More on Bupropion
- With alcoholBupropion and alcohol — is it safe to drink?
- With foodShould Bupropion be taken with food?
- Side effectsBupropion side effects: common, rare and warning signs
- Dosage guideBupropion dosage guide: how much to take and when
- OnsetHow fast does Bupropion start working?
- DurationHow long does Bupropion last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.