Norepinephrine-dopamine reuptake inhibitor (NDRI) antidepressant
Bupropion when planning pregnancy
For couples trying to conceive, every chronic medication deserves a careful pre-pregnancy review. Bupropion (Bupropion) at 75mg, 100mg, 150mg, 300mg may need to be continued, switched, or stopped before conception, depending on the active ingredient Bupropion and the indication. The right answer is rarely the same for everyone and rarely "just stop the medication."
Pre-conception review of Bupropion
According to the prescribing information for Bupropion, the pre-conception decision balances the risk of the medication during pregnancy against the consequences of leaving the underlying condition untreated. Some Norepinephrine-dopamine reuptake inhibitor (NDRI) antidepressant medications are continued safely through pregnancy; others are switched to safer alternatives before conception or in early pregnancy. Bupropion inhibits the reuptake of norepinephrine and dopamine, with much weaker effect on serotonin reuptake.
Effect on fertility itself
Some medications affect fertility directly — by altering ovulation, sperm parameters, hormonal balance or libido. Whether Bupropion has any documented effect on fertility depends on Bupropion; the prescribing information notes any data. Anyone trying to conceive should discuss Bupropion with the prescriber and a fertility specialist if conception is taking longer than expected.
Frequently asked questions
Should I stop Bupropion before trying to conceive? ▾
It depends on Bupropion and the indication. For some medications the answer is yes — switch to a safer alternative weeks before conception. For others, continuation is safe and preferable. The prescriber decides based on the full clinical picture.
Does Bupropion affect male fertility? ▾
Effects on male fertility depend on the active ingredient. Some medications in Norepinephrine-dopamine reuptake inhibitor (NDRI) antidepressant affect sperm parameters or libido; others have no documented effect. The prescribing information for Bupropion states what is known. If conception is delayed, a semen analysis can clarify whether Bupropion is contributing.
Products containing Bupropion
More on Bupropion
- With alcoholBupropion and alcohol — is it safe to drink?
- With foodShould Bupropion be taken with food?
- Side effectsBupropion side effects: common, rare and warning signs
- Dosage guideBupropion dosage guide: how much to take and when
- OnsetHow fast does Bupropion start working?
- DurationHow long does Bupropion last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.