Phosphodiesterase type 5 (PDE5) inhibitor
Skin side effects of Avanafil: rash, dryness, photosensitivity
Skin reactions are among the most visible side effects of medication and range from minor cosmetic concerns to medical emergencies. Avanafil (Avanafil) at 50mg, 100mg, 200mg may produce a range of skin effects depending on Avanafil; this page covers what is typical, what is rare, and what calls for stopping the medication.
Common skin effects of Avanafil
According to the prescribing information for Avanafil, common skin reactions include mild rash, dryness, mild itching, transient flushing and (for some agents) photosensitivity that makes the skin more sensitive to UV. Avanafil selectively inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum, increasing cGMP and enhancing nitric-oxide-mediated vasodilation in response to sexual stimulation. Most are mild, appear in the first weeks and resolve without intervention or with simple measures (moisturiser, sunscreen).
Serious skin reactions
Severe skin reactions — Stevens-Johnson syndrome, toxic epidermal necrolysis, drug-induced hypersensitivity syndrome — are rare but life-threatening. Warning signs are a rash with fever, mucosal involvement (mouth, eyes), skin peeling, or rapidly spreading rash. Any of these on Avanafil at 50mg, 100mg, 200mg is a medical emergency and reason to stop the medication and seek immediate care.
Frequently asked questions
Is a rash on Avanafil dangerous? ▾
Most rashes on Avanafil at 50mg, 100mg, 200mg are mild and resolve. A rash with fever, mucosal involvement, blistering or rapid spread is not — it requires emergency evaluation and stopping the medication.
Can Avanafil cause sunburn or photosensitivity? ▾
Some medications including a subset of Phosphodiesterase type 5 (PDE5) inhibitor agents increase UV sensitivity, making sunburn occur faster. The prescribing information for Avanafil lists this when documented. Sunscreen and avoiding peak sun exposure manage the risk.
Products containing Avanafil
More on Avanafil
- With alcoholAvanafil and alcohol — is it safe to drink?
- With foodShould Avanafil be taken with food?
- Side effectsAvanafil side effects: common, rare and warning signs
- Dosage guideAvanafil dosage guide: how much to take and when
- OnsetHow fast does Avanafil start working?
- DurationHow long does Avanafil last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.