Phosphodiesterase type 5 (PDE5) inhibitor
Avanafil dosage guide: how much to take and when
Choosing the right dose of Avanafil (Avanafil) is the most important practical decision after starting therapy. Avanafil is supplied as tablet in 50mg, 100mg, 200mg, and the right dose for a given person depends on the indication, age, comorbidities and tolerance to the active ingredient Avanafil.
Starting dose and titration
According to the prescribing information, most adults begin Avanafil at the lowest available strength of 50mg, 100mg, 200mg and titrate up only if symptom control is insufficient and tolerability is good. Higher doses are reserved for selected cases. Older adults, people with renal or hepatic impairment, and those taking interacting medications should usually start at the lowest dose.
When to adjust
Dose adjustment is guided by symptom response and side effect burden, not by arbitrary schedules. Avanafil selectively inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum, increasing cGMP and enhancing nitric-oxide-mediated vasodilation in response to sexual stimulation. If side effects are limiting at a given dose, going down a step is usually preferred over stopping abruptly. If the response is incomplete after several weeks, a higher dose can be tried under medical supervision.
Frequently asked questions
What is the standard starting dose of Avanafil? ▾
Most adults start Avanafil at the lowest strength of 50mg, 100mg, 200mg, with adjustment based on symptom response and tolerance. Older adults and those with reduced kidney or liver function generally start lower. The prescriber decides the exact starting dose for each person.
Can I take a higher dose of Avanafil if it isn't working? ▾
Higher doses of Avanafil should only be used after consulting the prescriber. Doubling on your own is unsafe, especially with active ingredients in the Phosphodiesterase type 5 (PDE5) inhibitor class. The prescriber can confirm whether titration is appropriate or whether the medication needs to be changed.
Products containing Avanafil
More on Avanafil
- With alcoholAvanafil and alcohol — is it safe to drink?
- With foodShould Avanafil be taken with food?
- Side effectsAvanafil side effects: common, rare and warning signs
- OnsetHow fast does Avanafil start working?
- DurationHow long does Avanafil last?
- Missed doseWhat to do if you miss a dose of Avanafil
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.