Phosphodiesterase type 5 (PDE5) inhibitor
Avanafil when planning pregnancy
For couples trying to conceive, every chronic medication deserves a careful pre-pregnancy review. Avanafil (Avanafil) at 50mg, 100mg, 200mg may need to be continued, switched, or stopped before conception, depending on the active ingredient Avanafil and the indication. The right answer is rarely the same for everyone and rarely "just stop the medication."
Pre-conception review of Avanafil
According to the prescribing information for Avanafil, the pre-conception decision balances the risk of the medication during pregnancy against the consequences of leaving the underlying condition untreated. Some Phosphodiesterase type 5 (PDE5) inhibitor medications are continued safely through pregnancy; others are switched to safer alternatives before conception or in early pregnancy. Avanafil selectively inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum, increasing cGMP and enhancing nitric-oxide-mediated vasodilation in response to sexual stimulation.
Effect on fertility itself
Some medications affect fertility directly — by altering ovulation, sperm parameters, hormonal balance or libido. Whether Avanafil has any documented effect on fertility depends on Avanafil; the prescribing information notes any data. Anyone trying to conceive should discuss Avanafil with the prescriber and a fertility specialist if conception is taking longer than expected.
Frequently asked questions
Should I stop Avanafil before trying to conceive? ▾
It depends on Avanafil and the indication. For some medications the answer is yes — switch to a safer alternative weeks before conception. For others, continuation is safe and preferable. The prescriber decides based on the full clinical picture.
Does Avanafil affect male fertility? ▾
Effects on male fertility depend on the active ingredient. Some medications in Phosphodiesterase type 5 (PDE5) inhibitor affect sperm parameters or libido; others have no documented effect. The prescribing information for Avanafil states what is known. If conception is delayed, a semen analysis can clarify whether Avanafil is contributing.
Products containing Avanafil
More on Avanafil
- With alcoholAvanafil and alcohol — is it safe to drink?
- With foodShould Avanafil be taken with food?
- Side effectsAvanafil side effects: common, rare and warning signs
- Dosage guideAvanafil dosage guide: how much to take and when
- OnsetHow fast does Avanafil start working?
- DurationHow long does Avanafil last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.