Tricyclic antidepressant (TCA)
Amitriptyline for athletes: anti-doping and performance
Athletes in regulated competitive sport face an additional layer of medication review beyond clinical considerations: whether Amitriptyline (Amitriptyline) is permitted under anti-doping rules, requires a Therapeutic Use Exemption, or is on the prohibited list at 10mg, 25mg, 50mg, 75mg, 100mg. The active ingredient Amitriptyline determines the answer; brand or generic version is irrelevant to anti-doping classification.
Anti-doping status of Amitriptyline
The WADA Prohibited List and equivalent national lists are updated annually. Amitriptyline may be permitted at all times, prohibited in-competition only, prohibited at all times, or require a TUE depending on the agent and the sport. Some otherwise-routine medications are restricted at competition because of their pharmacological effects on cardiovascular, neuromuscular or hormonal systems. Amitriptyline inhibits the reuptake of serotonin and noradrenaline at central synapses, raising synaptic levels of both neurotransmitters.
TUE and practical guidance
According to anti-doping authorities, an athlete who needs a prohibited or restricted medication for a legitimate medical reason can apply for a Therapeutic Use Exemption before using it. The application requires medical documentation and may need to be approved before competition. Athletes should always check the most recent WADA list and their sport's federation rules before starting Amitriptyline at 10mg, 25mg, 50mg, 75mg, 100mg.
Frequently asked questions
Is Amitriptyline banned in sport? ▾
Whether Amitriptyline is banned depends on Amitriptyline and the most recent WADA Prohibited List. Some agents are permitted, some restricted in-competition, some prohibited at all times. Always check the current list and TUE requirements before competition.
Will Amitriptyline affect my performance? ▾
Performance effects depend on the medication and the sport. Some medications can mildly impair physical or cognitive performance through their side effects; others are essentially neutral at 10mg, 25mg, 50mg, 75mg, 100mg. Athletes should expect to experiment with timing relative to training in the first weeks.
Products containing Amitriptyline
More on Amitriptyline
- With alcoholAmitriptyline and alcohol — is it safe to drink?
- With foodShould Amitriptyline be taken with food?
- Side effectsAmitriptyline side effects: common, rare and warning signs
- Dosage guideAmitriptyline dosage guide: how much to take and when
- OnsetHow fast does Amitriptyline start working?
- DurationHow long does Amitriptyline last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.