Prostaglandin E1 (PGE1)
What to do if you miss a dose of Alprostadil
Missing a dose of Alprostadil (Alprostadil) is common — most people will skip a dose at some point during a course. The right action depends on how long since the missed dose and whether Alprostadil is taken event-driven or daily at 10mcg, 20mcg, 40mcg. The wrong action — doubling up — is not recommended.
For daily Alprostadil
If Alprostadil is taken daily for a chronic condition, take the missed dose as soon as you remember, unless it is almost time for the next scheduled dose. In that case skip the missed dose and continue normally. According to the prescribing information for Alprostadil, two doses should never be taken close together to "make up" for a miss.
For event-driven Alprostadil
If Alprostadil is used as needed (not on a fixed schedule), there is no "missed dose" in the conventional sense — simply take the planned dose when needed and observe the recommended gap before re-dosing. Alprostadil binds prostaglandin E receptors on smooth muscle of the corpus cavernosum, triggering cAMP-mediated relaxation of cavernosal smooth muscle independent of the nitric oxide pathway used by P…
Frequently asked questions
Should I double the dose if I missed Alprostadil? ▾
No. Doubling doses of Alprostadil to compensate is not recommended at any 10mcg, 20mcg, 40mcg strength and increases the risk of side effects without improving efficacy. Take the next scheduled dose normally.
How many missed doses are too many? ▾
Occasional missed doses of Alprostadil are usually inconsequential. Repeated missed doses can compromise the therapeutic effect — for chronic conditions like those treated with Prostaglandin E1 (PGE1), consistent dosing matters. If adherence is hard, discuss reminders, simpler schedules or alternative formulations with the prescriber.
Products containing Alprostadil
More on Alprostadil
- With alcoholAlprostadil and alcohol — is it safe to drink?
- With foodShould Alprostadil be taken with food?
- Side effectsAlprostadil side effects: common, rare and warning signs
- Dosage guideAlprostadil dosage guide: how much to take and when
- OnsetHow fast does Alprostadil start working?
- DurationHow long does Alprostadil last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.