Prostaglandin E1 (PGE1)
Alprostadil in Spain: prescription, brands, pricing
This page summarises the situation of Alprostadil in Spain under AEMPS (Agencia Española de Medicamentos y Productos Sanitarios): prescription status, available brands and generics, pharmacy dispensing, and online options in EUR. Alprostadil belongs to the Prostaglandin E1 (PGE1) class.
- Regulator
- AEMPS (Agencia Española de Medicamentos y Productos Sanitarios)
- Currency
- EUR
About Alprostadil
Alprostadil is approved for erectile dysfunction of vasculogenic, neurogenic, psychogenic or mixed aetiology in adult men. In Spain, most active medications require a prescription, with the SNS (national health system) covering a portion based on the patient's contribution group. Receta electrónica is widely used.
Mechanism and action
Alprostadil binds prostaglandin E receptors on smooth muscle of the corpus cavernosum, triggering cAMP-mediated relaxation of cavernosal smooth muscle independent of the nitric oxide pathway used by PDE5 inhibitors.
Brands and generics in Spain
In Spain, Alprostadil is typically dispensed as one internationally recognised brand along with their corresponding authorised generics. Spanish farmacias are typically independent and tightly regulated; the green cross signage marks every authorised pharmacy. Pharmacist consultation is normalised and often the first point of healthcare contact. Brand-to-generic substitution is decided by the pharmacist under local AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) equivalence rules, and the price difference in EUR is usually substantial.
Online and tele-prescribing access
Online sale of prescription medication is restricted in Spain — only physical farmacias and AEMPS-authorised online channels for non-prescription medication are permitted. Tele-prescribing has expanded since 2020. For Alprostadil specifically, the legal online options in Spain depend on its Rx-or-OTC classification under AEMPS (Agencia Española de Medicamentos y Productos Sanitarios).
Frequently asked questions
Is Alprostadil available in Spain? ▾
Yes — Alprostadil and its brands are available in Spain through pharmacies authorised by AEMPS (Agencia Española de Medicamentos y Productos Sanitarios), in various strengths depending on the commercial product. Authorised generics offer a lower-cost alternative with the same active substance.
Do I need a prescription for Alprostadil in Spain? ▾
In Spain, most active medications require a prescription, with the SNS (national health system) covering a portion based on the patient's contribution group. Receta electrónica is widely used. The exact status of Alprostadil (Rx or OTC) is determined by AEMPS (Agencia Española de Medicamentos y Productos Sanitarios); most active ingredients in the Prostaglandin E1 (PGE1) class require prescription, although there are exceptions by country and formulation.
How much does Alprostadil cost in Spain? ▾
The price in EUR depends on the manufacturer (brand vs authorised generic), the strength and the pack size. Generics are typically substantially cheaper than brands and serve as the economic reference for ongoing use.
Products with Alprostadil in Spain
Alprostadil in other countries
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.