Prostaglandin E1 (PGE1)
Alprostadil in Australia: prescription, brands, pricing
This page summarises the situation of Alprostadil in Australia under TGA (Therapeutic Goods Administration): prescription status, available brands and generics, pharmacy dispensing, and online options in AUD. Alprostadil belongs to the Prostaglandin E1 (PGE1) class.
- Regulator
- TGA (Therapeutic Goods Administration)
- Currency
- AUD
About Alprostadil
Alprostadil is approved for erectile dysfunction of vasculogenic, neurogenic, psychogenic or mixed aetiology in adult men. Australia's medications are scheduled S1 through S10; Schedule 4 (prescription only) and Schedule 8 (controlled drugs) require written or e-prescriptions. The Pharmaceutical Benefits Scheme (PBS) subsidises most prescription costs to a fixed patient co-payment.
Mechanism and action
Alprostadil binds prostaglandin E receptors on smooth muscle of the corpus cavernosum, triggering cAMP-mediated relaxation of cavernosal smooth muscle independent of the nitric oxide pathway used by PDE5 inhibitors.
Brands and generics in Australia
In Australia, Alprostadil is typically dispensed as one internationally recognised brand along with their corresponding authorised generics. Australian pharmacies (Chemist Warehouse, Priceline Pharmacy, TerryWhite Chemmart and many independents) are regulated state-by-state. Pharmacist consultation is a core part of dispensing, with several states allowing pharmacists to prescribe for minor ailments under structured programmes. Brand-to-generic substitution is decided by the pharmacist under local TGA (Therapeutic Goods Administration) equivalence rules, and the price difference in AUD is usually substantial.
Online and tele-prescribing access
Online prescription dispensing in Australia operates through TGA-registered pharmacies and tele-prescribing platforms that have expanded since 2020. Personal importation of prescription medication is allowed under limited conditions for genuine personal use under the TGA's Personal Importation Scheme. For Alprostadil specifically, the legal online options in Australia depend on its Rx-or-OTC classification under TGA (Therapeutic Goods Administration).
Frequently asked questions
Is Alprostadil available in Australia? ▾
Yes — Alprostadil and its brands are available in Australia through pharmacies authorised by TGA (Therapeutic Goods Administration), in various strengths depending on the commercial product. Authorised generics offer a lower-cost alternative with the same active substance.
Do I need a prescription for Alprostadil in Australia? ▾
Australia's medications are scheduled S1 through S10; Schedule 4 (prescription only) and Schedule 8 (controlled drugs) require written or e-prescriptions. The Pharmaceutical Benefits Scheme (PBS) subsidises most prescription costs to a fixed patient co-payment. The exact status of Alprostadil (Rx or OTC) is determined by TGA (Therapeutic Goods Administration); most active ingredients in the Prostaglandin E1 (PGE1) class require prescription, although there are exceptions by country and formulation.
How much does Alprostadil cost in Australia? ▾
The price in AUD depends on the manufacturer (brand vs authorised generic), the strength and the pack size. Generics are typically substantially cheaper than brands and serve as the economic reference for ongoing use.
Products with Alprostadil in Australia
Alprostadil in other countries
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.