What to do if Prometrium is in shortage — for Colombia
Drug shortages happen periodically — manufacturing issues, supply chain disruptions, regulatory holds — and Prometrium (Progesterone) may become temporarily unavailable in some pharmacies or countries. For chronic users at 100mg, 200mg, knowing how to handle a shortage prevents unnecessary treatment interruption.
Colombia context
Drug shortages in Colombia are tracked by Invima (National Food and Drug Surveillance Institute) when significant. For Prometrium, shortage of one strength or one manufacturer rarely means total unavailability of Progesterone — authorised generics or alternative manufacturers usually fill the gap, with the pharmacist coordinating substitution and the prescriber confirming any formulation change at 100mg, 200mg.
- Regulator
- Invima (National Food and Drug Surveillance Institute)
- Currency
- COP
How shortages work for Prometrium
When Prometrium is in shortage, the pharmacist usually has several options: dispense an authorised generic of Progesterone, source from a different manufacturer of the same active ingredient, suggest a different formulation (e.g. liquid, dispersible) or, in extended shortages, ask the prescriber to consider an alternative Hormones and Birth Control agent. Progesterone in Prometrium binds to progesterone receptors and modulates gene expression in reproductive and other tissues.
Practical steps
According to general pharmacy practice, the first step in a Prometrium shortage is to ask the pharmacist about authorised generic availability — most shortages affect a single brand or strength, not the entire supply of Progesterone at 100mg, 200mg. The prescriber should be informed if the pharmacist needs to substitute or change formulation. Stockpiling or buying extra outside regulated channels is not the right response.
Frequently asked questions
What do I do if my pharmacy doesn't have Prometrium? ▾
Ask the pharmacist whether an authorised generic of Progesterone is available — usually yes — or whether another pharmacy in the area has stock of Prometrium at 100mg, 200mg. The pharmacist can also contact the prescriber if a formulation switch is needed.
Will Prometrium come back in stock? ▾
Most shortages are resolved within weeks to months as manufacturing or supply issues are fixed. Until then, the authorised generic of Progesterone is the standard alternative and is clinically equivalent to Prometrium at the same 100mg, 200mg strength.
What to do if Prometrium is in shortage in other countries
- the United StatesFDA (Food and Drug Administration)
- the United KingdomMHRA (Medicines and Healthcare products Regulatory Agency)
- SpainAEMPS (Agencia Española de Medicamentos y Productos Sanitarios)
- MexicoCOFEPRIS (Comisión Federal para la Protección contra Riesgos Sanitarios)
- ArgentinaANMAT (Administración Nacional de Medicamentos, Alimentos y Tecnología Médica)
- GermanyBfArM (Bundesinstitut für Arzneimittel und Medizinprodukte)
- FranceANSM (Agence nationale de sécurité du médicament et des produits de santé)
- ItalyAIFA (Agenzia Italiana del Farmaco)
- BrazilANVISA (Agência Nacional de Vigilância Sanitária)
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.