Wellbutrin when planning pregnancy
For couples trying to conceive, every chronic medication deserves a careful pre-pregnancy review. Wellbutrin (Bupropion) at 75mg, 100mg, 150mg, 300mg may need to be continued, switched, or stopped before conception, depending on the active ingredient Bupropion and the indication. The right answer is rarely the same for everyone and rarely "just stop the medication."
Pre-conception review of Wellbutrin
According to the prescribing information for Bupropion, the pre-conception decision balances the risk of the medication during pregnancy against the consequences of leaving the underlying condition untreated. Some Anti-Depressants medications are continued safely through pregnancy; others are switched to safer alternatives before conception or in early pregnancy. Wellbutrin inhibits the reuptake of norepinephrine and dopamine, with much weaker effect on serotonin.
Effect on fertility itself
Some medications affect fertility directly — by altering ovulation, sperm parameters, hormonal balance or libido. Whether Wellbutrin has any documented effect on fertility depends on Bupropion; the prescribing information notes any data. Anyone trying to conceive should discuss Wellbutrin with the prescriber and a fertility specialist if conception is taking longer than expected.
Frequently asked questions
Should I stop Wellbutrin before trying to conceive? ▾
It depends on Bupropion and the indication. For some medications the answer is yes — switch to a safer alternative weeks before conception. For others, continuation is safe and preferable. The prescriber decides based on the full clinical picture.
Does Wellbutrin affect male fertility? ▾
Effects on male fertility depend on the active ingredient. Some medications in Anti-Depressants affect sperm parameters or libido; others have no documented effect. The prescribing information for Bupropion states what is known. If conception is delayed, a semen analysis can clarify whether Wellbutrin is contributing.
More on Wellbutrin
- With alcoholWellbutrin and alcohol — is it safe to drink?
- With foodShould Wellbutrin be taken with food?
- Side effectsWellbutrin side effects: common, rare and warning signs
- Dosage guideWellbutrin dosage guide: how much to take and when
- OnsetHow fast does Wellbutrin start working?
- DurationHow long does Wellbutrin last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.