How Synthroid affects libido and sex drive
Libido and sex drive are commonly affected by medications, sometimes intentionally (e.g. ED therapies) and sometimes as an unwelcome side effect. Synthroid (Levothyroxine) may or may not affect libido depending on Levothyroxine; this page outlines what is documented at 25mcg, 50mcg, 75mcg, 100mcg, 150mcg and what users typically report.
Documented effects of Synthroid on libido
Some medications in Hormones and Birth Control are designed specifically to affect sexual function; for those, libido changes are expected and central to the indication. Others have libido changes as side effects of altered hormones, mood, energy or autonomic function. According to the prescribing information for Levothyroxine, the documented frequency varies and is listed in the side-effect profile.
Managing libido changes
For unwanted libido suppression, the right response often depends on whether the issue is the medication itself, the underlying condition, fatigue, or relationship factors. Levothyroxine replaces deficient endogenous thyroxine, which is converted in tissues to the active hormone triiodothyronine (T3) by deiodinase enzymes. A dose review, a switch within the same class, or addressing other contributors are all reasonable strategies and should be discussed with the prescriber rather than self-managed by stopping Synthroid at 25mcg, 50mcg, 75mcg, 100mcg, 150mcg.
Frequently asked questions
Does Synthroid lower libido? ▾
Some users on Synthroid report reduced libido, some report no change, and a few — particularly on indications targeting sexual function — report improvement. Whether this happens depends on Levothyroxine and individual factors. The prescriber can review options if libido changes are persistent or distressing.
Can libido recover after stopping Synthroid? ▾
For most users, libido changes attributable to Synthroid resolve within weeks of stopping the medication, though the timeline varies by active ingredient and individual. Persistent changes after stopping warrant medical evaluation, as the underlying condition may be the contributing factor.
More on Synthroid
- With alcoholSynthroid and alcohol — is it safe to drink?
- With foodShould Synthroid be taken with food?
- Side effectsSynthroid side effects: common, rare and warning signs
- Dosage guideSynthroid dosage guide: how much to take and when
- OnsetHow fast does Synthroid start working?
- DurationHow long does Synthroid last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.