Synthroid when planning pregnancy
For couples trying to conceive, every chronic medication deserves a careful pre-pregnancy review. Synthroid (Levothyroxine) at 25mcg, 50mcg, 75mcg, 100mcg, 150mcg may need to be continued, switched, or stopped before conception, depending on the active ingredient Levothyroxine and the indication. The right answer is rarely the same for everyone and rarely "just stop the medication."
Pre-conception review of Synthroid
According to the prescribing information for Levothyroxine, the pre-conception decision balances the risk of the medication during pregnancy against the consequences of leaving the underlying condition untreated. Some Hormones and Birth Control medications are continued safely through pregnancy; others are switched to safer alternatives before conception or in early pregnancy. Levothyroxine replaces deficient endogenous thyroxine, which is converted in tissues to the active hormone triiodothyronine (T3) by deiodinase enzymes.
Effect on fertility itself
Some medications affect fertility directly — by altering ovulation, sperm parameters, hormonal balance or libido. Whether Synthroid has any documented effect on fertility depends on Levothyroxine; the prescribing information notes any data. Anyone trying to conceive should discuss Synthroid with the prescriber and a fertility specialist if conception is taking longer than expected.
Frequently asked questions
Should I stop Synthroid before trying to conceive? ▾
It depends on Levothyroxine and the indication. For some medications the answer is yes — switch to a safer alternative weeks before conception. For others, continuation is safe and preferable. The prescriber decides based on the full clinical picture.
Does Synthroid affect male fertility? ▾
Effects on male fertility depend on the active ingredient. Some medications in Hormones and Birth Control affect sperm parameters or libido; others have no documented effect. The prescribing information for Levothyroxine states what is known. If conception is delayed, a semen analysis can clarify whether Synthroid is contributing.
More on Synthroid
- With alcoholSynthroid and alcohol — is it safe to drink?
- With foodShould Synthroid be taken with food?
- Side effectsSynthroid side effects: common, rare and warning signs
- Dosage guideSynthroid dosage guide: how much to take and when
- OnsetHow fast does Synthroid start working?
- DurationHow long does Synthroid last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.