Prometrium dosage guide: how much to take and when
Choosing the right dose of Prometrium (Progesterone) is the most important practical decision after starting therapy. Prometrium is supplied as capsule in 100mg, 200mg, and the right dose for a given person depends on the indication, age, comorbidities and tolerance to the active ingredient Progesterone.
Starting dose and titration
According to the prescribing information, most adults begin Prometrium at the lowest available strength of 100mg, 200mg and titrate up only if symptom control is insufficient and tolerability is good. Higher doses are reserved for selected cases. Older adults, people with renal or hepatic impairment, and those taking interacting medications should usually start at the lowest dose.
When to adjust
Dose adjustment is guided by symptom response and side effect burden, not by arbitrary schedules. Progesterone in Prometrium binds to progesterone receptors and modulates gene expression in reproductive and other tissues. If side effects are limiting at a given dose, going down a step is usually preferred over stopping abruptly. If the response is incomplete after several weeks, a higher dose can be tried under medical supervision.
Frequently asked questions
What is the standard starting dose of Prometrium? ▾
Most adults start Prometrium at the lowest strength of 100mg, 200mg, with adjustment based on symptom response and tolerance. Older adults and those with reduced kidney or liver function generally start lower. The prescriber decides the exact starting dose for each person.
Can I take a higher dose of Prometrium if it isn't working? ▾
Higher doses of Prometrium should only be used after consulting the prescriber. Doubling on your own is unsafe, especially with active ingredients in the Hormones and Birth Control class. The prescriber can confirm whether titration is appropriate or whether the medication needs to be changed.
More on Prometrium
- With alcoholPrometrium and alcohol — is it safe to drink?
- With foodShould Prometrium be taken with food?
- Side effectsPrometrium side effects: common, rare and warning signs
- OnsetHow fast does Prometrium start working?
- DurationHow long does Prometrium last?
- Missed doseWhat to do if you miss a dose of Prometrium
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.