Lexapro and surgery: what to do before and after
Surgery raises specific medication-management questions, and getting the answer right matters because both unintended drug interactions during anaesthesia and abrupt discontinuation of important chronic therapies carry risk. Whether Lexapro (Escitalopram) needs to be stopped before surgery, continued through, or paused for a defined window depends on Escitalopram and the type of procedure.
Before-surgery decision
For most chronic medications including many Anti-Depressants agents, the surgical team or anaesthetist makes the stop-or-continue decision during pre-op assessment. Considerations include bleeding risk, anaesthesia interactions, the urgency of the underlying condition and the type of procedure. According to most guidelines, surprises are avoided by listing all medications including Lexapro at 5mg, 10mg, 20mg on the pre-op form.
After surgery
Post-operative resumption of Lexapro depends on the surgical course, the medication's impact on recovery (e.g. wound healing, gastric tolerance, mobility) and any new prescriptions added after surgery. Lexapro acts by selectively inhibiting the serotonin reuptake transporter (SERT) at the synapse, increasing serotonin availability for postsynaptic receptors. Resuming on schedule is usually the goal as soon as oral intake and clinical stability allow.
Frequently asked questions
Do I need to stop Lexapro before surgery? ▾
It depends on Escitalopram and the procedure. The pre-op assessment is where this is decided, ideally a week or more before surgery. Bring the full medication list including Lexapro at 5mg, 10mg, 20mg so the team can advise.
When can I restart Lexapro after surgery? ▾
Resumption timing depends on the procedure, the recovery course and any interactions with new postoperative medications. Many patients restart Lexapro on the day of discharge or earlier; some need a longer pause. The surgical team or prescriber confirms the timing.
More on Lexapro
- With alcoholLexapro and alcohol — is it safe to drink?
- With foodShould Lexapro be taken with food?
- Side effectsLexapro side effects: common, rare and warning signs
- Dosage guideLexapro dosage guide: how much to take and when
- OnsetHow fast does Lexapro start working?
- DurationHow long does Lexapro last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.