Desyrel 50mg

Forms and dosages

Trazodone is supplied as immediate-release tablets in 50, 100, 150 and 300mg strengths. For insomnia, typical dosing is 25–100mg at bedtime, with most users finding 50mg sufficient. For depression, the dose is 150–300mg/day, often divided initially because of sedation. Take with food to reduce nausea and improve absorption. Bedtime dosing is standard for sleep; sedation makes daytime depression dosing impractical for most patients.

Indications

Desyrel (trazodone) is approved for major depressive disorder. It is widely used off-label for insomnia (most common modern use), depression with anxiety, post-traumatic stress disorder, and adjunctive use with SSRIs for sleep. According to current sleep guidelines, low-dose trazodone is one of several options for chronic insomnia, particularly when standard hypnotics (zolpidem, eszopiclone) are unsuitable due to dependence concerns.