Cymbalta 60mg

Forms and dosages

Cymbalta is supplied as opaque, two-toned delayed-release capsules. The recommended target dose for most indications is 60mg once daily; some users start at 30mg for the first week to improve tolerability before titrating up. For chronic pain indications, doses of 60–120mg daily are used. Capsules must be swallowed whole — never opened, crushed or chewed — because this destroys the enteric coating and exposes the active ingredient to gastric acid.

Indications

Cymbalta is approved for major depressive disorder, generalised anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia and chronic musculoskeletal pain. According to clinical guidelines, it is generally first-line when depression and pain coexist, and it is one of the preferred first-line agents for fibromyalgia and diabetic neuropathy regardless of mood symptoms.