Aygestin dosage guide: how much to take and when
Choosing the right dose of Aygestin (Norethindrone Acetate) is the most important practical decision after starting therapy. Aygestin is supplied as tablet in 5mg, and the right dose for a given person depends on the indication, age, comorbidities and tolerance to the active ingredient Norethindrone.
Starting dose and titration
According to the prescribing information, most adults begin Aygestin at the lowest available strength of 5mg and titrate up only if symptom control is insufficient and tolerability is good. Higher doses are reserved for selected cases. Older adults, people with renal or hepatic impairment, and those taking interacting medications should usually start at the lowest dose.
When to adjust
Dose adjustment is guided by symptom response and side effect burden, not by arbitrary schedules. Norethindrone binds to progesterone receptors and exerts progestational effects: thickening cervical mucus, suppressing the LH surge, thinning the endometrium and reducing endometrial implant activity… If side effects are limiting at a given dose, going down a step is usually preferred over stopping abruptly. If the response is incomplete after several weeks, a higher dose can be tried under medical supervision.
Frequently asked questions
What is the standard starting dose of Aygestin? ▾
Most adults start Aygestin at the lowest strength of 5mg, with adjustment based on symptom response and tolerance. Older adults and those with reduced kidney or liver function generally start lower. The prescriber decides the exact starting dose for each person.
Can I take a higher dose of Aygestin if it isn't working? ▾
Higher doses of Aygestin should only be used after consulting the prescriber. Doubling on your own is unsafe, especially with active ingredients in the Women's Sexual Health class. The prescriber can confirm whether titration is appropriate or whether the medication needs to be changed.
More on Aygestin
- With alcoholAygestin and alcohol — is it safe to drink?
- With foodShould Aygestin be taken with food?
- Side effectsAygestin side effects: common, rare and warning signs
- OnsetHow fast does Aygestin start working?
- DurationHow long does Aygestin last?
- Missed doseWhat to do if you miss a dose of Aygestin
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.