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Voltaren vs Yaz: side-by-side comparison

Voltaren (Diclofenac) 25mg tablet
Voltaren
vs
Yaz (Drospirenone/Ethinylestradiol) 3mg/0.02mg tablet
Yaz

Voltaren (Pain Relief Medications) and Yaz (Hormones and Birth Control) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Voltaren Yaz
Active ingredient Diclofenac Drospirenone
Manufacturer Novartis Bayer
Class Pain Relief Medications Hormones and Birth Control
Strengths 25mg, 50mg, 75mg, 100mg 3mg/0.02mg
Forms tablet, delayed-release tablet, topical gel, suppository tablet

What's the same

Voltaren and Yaz are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Voltaren belongs to Pain Relief Medications while Yaz belongs to Hormones and Birth Control. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Voltaren: Diclofenac reversibly inhibits cyclooxygenase enzymes COX-1 and COX-2, with somewhat greater selectivity for COX-2 than ibuprofen and naproxen. Yaz: Yaz prevents pregnancy through three mechanisms: ovulation suppression (the dominant effect), thickening of cervical mucus to impede sperm transit, and changes in endometrial receptivity.

When Voltaren is preferred

Voltaren is approved in adults for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute musculoskeletal pain, post-surgical pain, primary dysmenorrhoea, acute migraine and ureteric colic.

When Yaz is preferred

Yaz is approved for contraception in adult women requesting an oral contraceptive, treatment of premenstrual dysphoric disorder (PMDD), and treatment of moderate acne in women aged ≥14 who are also requesting contraception.

Frequently asked questions

Is Voltaren or Yaz better?

Voltaren and Yaz are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Voltaren to Yaz?

Switching between Voltaren and Yaz is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Voltaren and Yaz have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Voltaren comparisons

The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.