Plan B vs Evista: side-by-side comparison
Plan B (Levonorgestrel) and Evista (Raloxifene) both belong to the Hormones and Birth Control class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Plan B | Evista |
|---|---|---|
| Active ingredient | Levonorgestrel | Raloxifene |
| Manufacturer | Foundation Consumer Healthcare | Eli Lilly |
| Class | Hormones and Birth Control | Hormones and Birth Control |
| Strengths | 1.5mg | 60mg |
| Forms | tablet | tablet |
What's the same
Plan B and Evista both belong to the Hormones and Birth Control class and are used for partially overlapping indications. The active ingredients — Levonorgestrel vs Raloxifene — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Levonorgestrel vs Raloxifene), strengths (1.5mg vs 60mg), forms (tablet vs tablet), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Plan B: Plan B's primary mechanism is delaying or preventing ovulation when taken before the LH surge. Evista: Raloxifene binds estrogen receptors and produces tissue-selective effects: estrogen-agonist activity in bone (preserving bone mineral density) and on lipid metabolism (lowering LDL cholesterol), while exhibiting estrogen…
When Plan B is preferred
Plan B is indicated for emergency contraception after unprotected intercourse or known/suspected contraceptive failure, in women of reproductive age.
When Evista is preferred
Evista is approved for prevention and treatment of postmenopausal osteoporosis and for reduction of invasive breast cancer risk in postmenopausal women at increased risk.
Frequently asked questions
Is Plan B or Evista better? ▾
There is no single answer. Plan B and Evista both belong to the Hormones and Birth Control class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Plan B to Evista? ▾
Switching within the Hormones and Birth Control class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Plan B and Evista have the same side effects? ▾
They share many of the Hormones and Birth Control class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Plan B comparisons
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.