Cialis Professional vs Stendra: side-by-side comparison
Cialis Professional (Tadalafil) and Stendra (Avanafil) both belong to the Erectile Dysfunction (ED) class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Cialis Professional | Stendra |
|---|---|---|
| Active ingredient | Tadalafil | Avanafil |
| Manufacturer | Eli Lilly | Metuchen Pharmaceuticals |
| Class | Erectile Dysfunction (ED) | Erectile Dysfunction (ED) |
| Strengths | 20mg | 50mg, 100mg, 200mg |
| Forms | sublingual tablet | tablet |
What's the same
Cialis Professional and Stendra both belong to the Erectile Dysfunction (ED) class and are used for partially overlapping indications. The active ingredients — Tadalafil vs Avanafil — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Tadalafil vs Avanafil), strengths (20mg vs 50mg, 100mg, 200mg), forms (sublingual tablet vs tablet), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Cialis Professional: Tadalafil inhibits PDE5 in penile tissue and other vascular smooth muscle, allowing cyclic GMP produced during sexual arousal to accumulate, relaxing smooth muscle and increasing blood inflow. Stendra: Avanafil selectively inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum, increasing cGMP and enhancing nitric-oxide-mediated vasodilation in response to sexual stimulation.
When Cialis Professional is preferred
Cialis Professional is intended for adult men with erectile dysfunction.
When Stendra is preferred
Stendra is approved for erectile dysfunction in adult men.
Frequently asked questions
Is Cialis Professional or Stendra better? ▾
There is no single answer. Cialis Professional and Stendra both belong to the Erectile Dysfunction (ED) class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Cialis Professional to Stendra? ▾
Switching within the Erectile Dysfunction (ED) class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Cialis Professional and Stendra have the same side effects? ▾
They share many of the Erectile Dysfunction (ED) class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
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The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.