Caverject vs Viagra: side-by-side comparison
Caverject (Alprostadil) and Viagra (Sildenafil Citrate) both belong to the Erectile Dysfunction (ED) class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Caverject | Viagra |
|---|---|---|
| Active ingredient | Alprostadil | Sildenafil Citrate |
| Manufacturer | Pfizer | Pfizer |
| Class | Erectile Dysfunction (ED) | Erectile Dysfunction (ED) |
| Strengths | 10mcg, 20mcg, 40mcg | 25mg, 50mg, 100mg |
| Forms | injection | tablet |
What's the same
Caverject and Viagra both belong to the Erectile Dysfunction (ED) class and are used for partially overlapping indications. The active ingredients — Alprostadil vs Sildenafil Citrate — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Alprostadil vs Sildenafil Citrate), strengths (10mcg, 20mcg, 40mcg vs 25mg, 50mg, 100mg), forms (injection vs tablet), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Caverject: Alprostadil binds prostaglandin E receptors on smooth muscle of the corpus cavernosum, triggering cAMP-mediated relaxation of cavernosal smooth muscle independent of the nitric oxide pathway used by PDE5 inhibitors. Viagra: During sexual stimulation, nitric oxide is released in the corpus cavernosum and activates an enzyme that produces cyclic GMP.
When Caverject is preferred
Caverject is approved for erectile dysfunction of vasculogenic, neurogenic, psychogenic or mixed aetiology in adult men.
When Viagra is preferred
The medication is indicated in adult men for the treatment of erectile dysfunction, defined as the inability to achieve or maintain a penile erection sufficient for sexual activity.
Frequently asked questions
Is Caverject or Viagra better? ▾
There is no single answer. Caverject and Viagra both belong to the Erectile Dysfunction (ED) class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Caverject to Viagra? ▾
Switching within the Erectile Dysfunction (ED) class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Caverject and Viagra have the same side effects? ▾
They share many of the Erectile Dysfunction (ED) class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Caverject comparisons
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.