Caverject vs Cialis Daily: side-by-side comparison
Caverject (Alprostadil) and Cialis Daily (Tadalafil) both belong to the Erectile Dysfunction (ED) class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Caverject | Cialis Daily |
|---|---|---|
| Active ingredient | Alprostadil | Tadalafil |
| Manufacturer | Pfizer | Eli Lilly |
| Class | Erectile Dysfunction (ED) | Erectile Dysfunction (ED) |
| Strengths | 10mcg, 20mcg, 40mcg | 2.5mg, 5mg |
| Forms | injection | tablet |
What's the same
Caverject and Cialis Daily both belong to the Erectile Dysfunction (ED) class and are used for partially overlapping indications. The active ingredients — Alprostadil vs Tadalafil — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Alprostadil vs Tadalafil), strengths (10mcg, 20mcg, 40mcg vs 2.5mg, 5mg), forms (injection vs tablet), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Caverject: Alprostadil binds prostaglandin E receptors on smooth muscle of the corpus cavernosum, triggering cAMP-mediated relaxation of cavernosal smooth muscle independent of the nitric oxide pathway used by PDE5 inhibitors. Cialis Daily: PDE5 inhibition by tadalafil prevents the breakdown of cyclic GMP in penile and vascular smooth muscle.
When Caverject is preferred
Caverject is approved for erectile dysfunction of vasculogenic, neurogenic, psychogenic or mixed aetiology in adult men.
When Cialis Daily is preferred
Cialis Daily is approved in adult men for two indications: continuous treatment of erectile dysfunction, and treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH).
Frequently asked questions
Is Caverject or Cialis Daily better? ▾
There is no single answer. Caverject and Cialis Daily both belong to the Erectile Dysfunction (ED) class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Caverject to Cialis Daily? ▾
Switching within the Erectile Dysfunction (ED) class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Caverject and Cialis Daily have the same side effects? ▾
They share many of the Erectile Dysfunction (ED) class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Caverject comparisons
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.