Caverject vs Viagra Professional: side-by-side comparison
Caverject (Alprostadil) and Viagra Professional (Sildenafil Citrate) both belong to the Erectile Dysfunction (ED) class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Caverject | Viagra Professional |
|---|---|---|
| Active ingredient | Alprostadil | Sildenafil Citrate |
| Manufacturer | Pfizer | Pfizer |
| Class | Erectile Dysfunction (ED) | Erectile Dysfunction (ED) |
| Strengths | 10mcg, 20mcg, 40mcg | 100mg |
| Forms | injection | sublingual tablet |
What's the same
Caverject and Viagra Professional both belong to the Erectile Dysfunction (ED) class and are used for partially overlapping indications. The active ingredients — Alprostadil vs Sildenafil Citrate — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Alprostadil vs Sildenafil Citrate), strengths (10mcg, 20mcg, 40mcg vs 100mg), forms (injection vs sublingual tablet), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Caverject: Alprostadil binds prostaglandin E receptors on smooth muscle of the corpus cavernosum, triggering cAMP-mediated relaxation of cavernosal smooth muscle independent of the nitric oxide pathway used by PDE5 inhibitors. Viagra Professional: Sildenafil citrate inhibits PDE5, allowing the cyclic GMP produced during sexual arousal to accumulate in penile tissue, which relaxes the smooth muscle of the penile arteries and increases blood inflow.
When Caverject is preferred
Caverject is approved for erectile dysfunction of vasculogenic, neurogenic, psychogenic or mixed aetiology in adult men.
When Viagra Professional is preferred
Viagra Professional is intended for adult men with erectile dysfunction.
Frequently asked questions
Is Caverject or Viagra Professional better? ▾
There is no single answer. Caverject and Viagra Professional both belong to the Erectile Dysfunction (ED) class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Caverject to Viagra Professional? ▾
Switching within the Erectile Dysfunction (ED) class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Caverject and Viagra Professional have the same side effects? ▾
They share many of the Erectile Dysfunction (ED) class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Caverject comparisons
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.