Caverject vs Cialis Super Active: side-by-side comparison
Caverject (Alprostadil) and Cialis Super Active (Tadalafil) both belong to the Erectile Dysfunction (ED) class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Caverject | Cialis Super Active |
|---|---|---|
| Active ingredient | Alprostadil | Tadalafil |
| Manufacturer | Pfizer | Eli Lilly |
| Class | Erectile Dysfunction (ED) | Erectile Dysfunction (ED) |
| Strengths | 10mcg, 20mcg, 40mcg | 20mg |
| Forms | injection | soft gelatin capsule |
What's the same
Caverject and Cialis Super Active both belong to the Erectile Dysfunction (ED) class and are used for partially overlapping indications. The active ingredients — Alprostadil vs Tadalafil — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Alprostadil vs Tadalafil), strengths (10mcg, 20mcg, 40mcg vs 20mg), forms (injection vs soft gelatin capsule), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Caverject: Alprostadil binds prostaglandin E receptors on smooth muscle of the corpus cavernosum, triggering cAMP-mediated relaxation of cavernosal smooth muscle independent of the nitric oxide pathway used by PDE5 inhibitors. Cialis Super Active: Tadalafil inhibits PDE5 in penile tissue during sexual arousal, allowing cyclic GMP to accumulate, smooth muscle to relax and blood inflow to increase.
When Caverject is preferred
Caverject is approved for erectile dysfunction of vasculogenic, neurogenic, psychogenic or mixed aetiology in adult men.
When Cialis Super Active is preferred
Cialis Super Active is intended for adult men with erectile dysfunction.
Frequently asked questions
Is Caverject or Cialis Super Active better? ▾
There is no single answer. Caverject and Cialis Super Active both belong to the Erectile Dysfunction (ED) class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Caverject to Cialis Super Active? ▾
Switching within the Erectile Dysfunction (ED) class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Caverject and Cialis Super Active have the same side effects? ▾
They share many of the Erectile Dysfunction (ED) class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Caverject comparisons
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.