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Avodart vs Lexapro: side-by-side comparison

Avodart (Dutasteride) 0.5mg capsule
Avodart
vs
Lexapro (Escitalopram) 5mg tablet
Lexapro

Avodart (Male and Female Pattern Hair Loss) and Lexapro (Anti-Depressants) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Avodart Lexapro
Active ingredient Dutasteride Escitalopram
Manufacturer GlaxoSmithKline Forest/Allergan
Class Male and Female Pattern Hair Loss Anti-Depressants
Strengths 0.5mg 5mg, 10mg, 20mg
Forms capsule tablet

What's the same

Avodart and Lexapro are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Avodart belongs to Male and Female Pattern Hair Loss while Lexapro belongs to Anti-Depressants. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Avodart: Avodart inhibits both isoforms of 5α-reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT). Lexapro: Lexapro acts by selectively inhibiting the serotonin reuptake transporter (SERT) at the synapse, increasing serotonin availability for postsynaptic receptors.

When Avodart is preferred

Avodart is approved for the treatment of moderate to severe symptomatic benign prostatic hyperplasia, alone or in combination with the alpha-blocker tamsulosin.

When Lexapro is preferred

Lexapro is approved for major depressive disorder and generalised anxiety disorder in adults and adolescents 12 years and older (depression) and adults (generalised anxiety).

Frequently asked questions

Is Avodart or Lexapro better?

Avodart and Lexapro are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Avodart to Lexapro?

Switching between Avodart and Lexapro is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Avodart and Lexapro have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Avodart comparisons

The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.