Antifungal Medications with antibiotics: interactions and safety
Antibiotic courses are common, short-term and often combined with chronic medications such as Antifungal Medications (Antifungal Medications). Most antibiotics do not interfere meaningfully with Fluconazole at 50mg, 100mg, 150mg, 200mg, but a few classes do, and a small number of combinations are best avoided.
Common antibiotic interactions
Macrolides (clarithromycin, erythromycin) and certain antifungals can inhibit hepatic metabolism (CYP3A4) and raise plasma levels of many medications including some Antifungal Medications agents. Rifampicin has the opposite effect, accelerating metabolism. Most penicillins, cephalosporins, fluoroquinolones and tetracyclines have no clinically meaningful interaction with Fluconazole at 50mg, 100mg, 150mg, 200mg.
Practical guidance
According to the prescribing information for Fluconazole, an antibiotic course should be reviewed by the prescriber or pharmacist for known interactions before Antifungal Medications is co-administered. Adjusted 50mg, 100mg, 150mg, 200mg dosing or temporary substitution is sometimes preferred for the duration of the antibiotic course.
Frequently asked questions
Can I take Antifungal Medications during an antibiotic course? ▾
For most common antibiotics, yes. A few classes — notably macrolides and azole antifungals — alter how Fluconazole is metabolised and may need a temporary 50mg, 100mg, 150mg, 200mg adjustment. The prescribing pharmacist should review any new antibiotic against the existing Antifungal Medications regimen.
Will antibiotics make Antifungal Medications stop working? ▾
Most antibiotics do not affect Antifungal Medications efficacy. Rifampicin and a few others can lower Fluconazole levels and reduce effect; in those cases the prescriber may adjust the dose during and shortly after the antibiotic course.
Medications in Antifungal Medications
More on Antifungal Medications
- With alcoholAntifungal Medications and alcohol — is it safe to drink?
- With foodShould Antifungal Medications be taken with food?
- Side effectsAntifungal Medications side effects: common, rare and warning signs
- For older adultsAntifungal Medications after 60: doses and safety in older adults
- For womenAntifungal Medications for women: indications and considerations
- For menAntifungal Medications for men: indications and considerations
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