Viagra vs Sildenafil Citrate: are they the same?
Viagra is a commercial brand whose active ingredient is exactly Sildenafil Citrate. This page explains what that means in practice: where they differ (brand, manufacturer, price, available strengths), why they are clinically equivalent, and when the brand or an authorised generic is the better choice.
Are they the same?
Yes — Viagra contains Sildenafil Citrate as its active ingredient. Talking about "Viagra" in clinical terms is the same as talking about Sildenafil Citrate at the dose strengths 25mg, 50mg, 100mg. The differences from the authorised generic are brand, manufacturer (Pfizer), excipients, tablet appearance and price — not the active molecule itself.
When Viagra is used
本剤は成人男性において性行為に十分な陰茎勃起を達成または維持できない状態と定義される勃起不全の治療に適応されます。女性、小児患者、または勃起不全の診断のない男性には適応されません。製造元の添付文書によれば、治療は臨床医が基礎原因と心血管適合性を評価した後にのみ検討すべきです。
Mechanisms compared
Because they share the same active ingredient, the mechanism is identical: 性的刺激中、陰茎海綿体で一酸化窒素が放出され、cGMPを産生する酵素を活性化します。cGMPは陰茎動脈の平滑筋を弛緩させ、血流増加と勃起を可能にします。シルデナフィルクエン酸塩はPDE5によるcGMPの分解を防ぎ、その作用を延長します。発現は通常30~60分以内であり、臨床試験によれば効果は最大4時間持続します。
Brand or generic — which to choose?
For most patients, authorised generics of Sildenafil Citrate are clinically equivalent substitutes for Viagra and typically cost substantially less. The practical differences are manufacturer, excipients (rarely matters except in specific sensitivities), tablet appearance and price. The brand is preferred by some patients for personal reasons or insurance coverage; the generic is the default when cost matters.
よくある質問
Is Viagra the same as Sildenafil Citrate? ▾
Clinically yes — Viagra is the brand and Sildenafil Citrate is its active ingredient. At equivalent doses (25mg, 50mg, 100mg) they produce the same effect. The difference is brand, manufacturer (Pfizer) and price.
Is generic Sildenafil Citrate as effective as Viagra? ▾
Yes. Authorised generics of Sildenafil Citrate must demonstrate bioequivalence to the brand. The active substance is the same; average effect is the same. Price is usually substantially lower.
Why does Viagra cost more than generic Sildenafil Citrate? ▾
The price difference reflects originator development costs, brand recognition and competition among generic manufacturers. The molecule is identical; the cost is not.
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