Cialis vs Tadalafil: are they the same?
Cialis is a commercial brand whose active ingredient is exactly Tadalafil. This page explains what that means in practice: where they differ (brand, manufacturer, price, available strengths), why they are clinically equivalent, and when the brand or an authorised generic is the better choice.
Are they the same?
Yes — Cialis contains Tadalafil as its active ingredient. Talking about "Cialis" in clinical terms is the same as talking about Tadalafil at the dose strengths 2.5mg, 5mg, 10mg, 20mg. The differences from the authorised generic are brand, manufacturer (Eli Lilly), excipients, tablet appearance and price — not the active molecule itself.
When Cialis is used
シアリスは成人男性の勃起不全治療に適応があります。また、前立腺肥大症に伴う下部尿路症状の治療にも承認されており、両方の適応がある場合は毎日投与5mg製剤で治療されます。本剤は女性、小児患者、または該当する診断のない男性には承認されていません。製造元の添付文書によれば、治療は心血管系の適合性および現在の併用薬の評価後に開始すべきです。
Mechanisms compared
Because they share the same active ingredient, the mechanism is identical: 性的刺激中、陰茎海綿体で一酸化窒素が放出され、サイクリックGMPを産生する酵素を活性化します。サイクリックGMPは陰茎動脈の平滑筋を弛緩させ、血流を増加させて勃起を支えます。タダラフィルはPDE5がサイクリックGMPを分解するのを防ぎ、その作用を延長します。作用発現は必要時投与後通常30~60分以内で、臨床試験によれば効果は最大36時間持続します — 承認されたPDE5阻害薬の中で最も長いウィンドウです。
Brand or generic — which to choose?
For most patients, authorised generics of Tadalafil are clinically equivalent substitutes for Cialis and typically cost substantially less. The practical differences are manufacturer, excipients (rarely matters except in specific sensitivities), tablet appearance and price. The brand is preferred by some patients for personal reasons or insurance coverage; the generic is the default when cost matters.
よくある質問
Is Cialis the same as Tadalafil? ▾
Clinically yes — Cialis is the brand and Tadalafil is its active ingredient. At equivalent doses (2.5mg, 5mg, 10mg, 20mg) they produce the same effect. The difference is brand, manufacturer (Eli Lilly) and price.
Is generic Tadalafil as effective as Cialis? ▾
Yes. Authorised generics of Tadalafil must demonstrate bioequivalence to the brand. The active substance is the same; average effect is the same. Price is usually substantially lower.
Why does Cialis cost more than generic Tadalafil? ▾
The price difference reflects originator development costs, brand recognition and competition among generic manufacturers. The molecule is identical; the cost is not.
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