Synthetic steroid (STEAR)
Tibolone and surgery: what to do before and after
Surgery raises specific medication-management questions, and getting the answer right matters because both unintended drug interactions during anaesthesia and abrupt discontinuation of important chronic therapies carry risk. Whether Tibolone (Tibolone) needs to be stopped before surgery, continued through, or paused for a defined window depends on Tibolone and the type of procedure.
Before-surgery decision
For most chronic medications including many Synthetic steroid (STEAR) agents, the surgical team or anaesthetist makes the stop-or-continue decision during pre-op assessment. Considerations include bleeding risk, anaesthesia interactions, the urgency of the underlying condition and the type of procedure. According to most guidelines, surprises are avoided by listing all medications including Tibolone at 2.5mg on the pre-op form.
After surgery
Post-operative resumption of Tibolone depends on the surgical course, the medication's impact on recovery (e.g. wound healing, gastric tolerance, mobility) and any new prescriptions added after surgery. Tibolone is a prodrug; on absorption it is rapidly converted to three active metabolites (3α-OH-tibolone, 3β-OH-tibolone and Δ4-tibolone) with different tissue-selective activity. Resuming on schedule is usually the goal as soon as oral intake and clinical stability allow.
Frequently asked questions
Do I need to stop Tibolone before surgery? ▾
It depends on Tibolone and the procedure. The pre-op assessment is where this is decided, ideally a week or more before surgery. Bring the full medication list including Tibolone at 2.5mg so the team can advise.
When can I restart Tibolone after surgery? ▾
Resumption timing depends on the procedure, the recovery course and any interactions with new postoperative medications. Many patients restart Tibolone on the day of discharge or earlier; some need a longer pause. The surgical team or prescriber confirms the timing.
Products containing Tibolone
More on Tibolone
- With alcoholTibolone and alcohol — is it safe to drink?
- With foodShould Tibolone be taken with food?
- Side effectsTibolone side effects: common, rare and warning signs
- Dosage guideTibolone dosage guide: how much to take and when
- OnsetHow fast does Tibolone start working?
- DurationHow long does Tibolone last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.