Synthetic steroid (STEAR)
Tibolone and pregnancy: what we know
Pregnancy and breastfeeding are special periods where every medication choice deserves careful review. Tibolone (Tibolone) is no exception. The prescribing information for Tibolone provides specific guidance, and the right decision depends on the indication, alternatives, gestational stage and the woman's overall medical picture.
Pregnancy safety data for Tibolone
According to the prescribing information for Tibolone, the available human data in pregnancy may be limited, supportive, or restrictive depending on the molecule. Some Synthetic steroid (STEAR) agents are routinely used in pregnancy when needed; others are avoided. The risk-benefit calculation includes the importance of treating the underlying condition and the consequences of leaving it untreated.
Breastfeeding considerations
Breastfeeding considerations are usually separate from pregnancy considerations. Some active ingredients pass into breast milk in negligible amounts; others are present at levels that warrant caution. Tibolone is a prodrug; on absorption it is rapidly converted to three active metabolites (3α-OH-tibolone, 3β-OH-tibolone and Δ4-tibolone) with different tissue-selective activity. The prescriber weighs the benefit of breastfeeding, the importance of Tibolone, and the availability of alternative therapies.
Frequently asked questions
Can I take Tibolone during pregnancy? ▾
Whether Tibolone can be taken in pregnancy depends on the active ingredient Tibolone, the indication and the gestational stage. The prescribing information should be consulted, and any pregnancy or planned pregnancy should be discussed with the prescriber before starting or continuing Tibolone at 2.5mg.
Will Tibolone affect my baby? ▾
Effects on the fetus or breastfed infant depend on whether the active ingredient Tibolone crosses the placenta or enters breast milk and at what concentrations. Most decisions are individualised; some women continue Tibolone during pregnancy when benefits clearly outweigh known risks, others switch.
Products containing Tibolone
More on Tibolone
- With alcoholTibolone and alcohol — is it safe to drink?
- With foodShould Tibolone be taken with food?
- Side effectsTibolone side effects: common, rare and warning signs
- Dosage guideTibolone dosage guide: how much to take and when
- OnsetHow fast does Tibolone start working?
- DurationHow long does Tibolone last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.