Benzodiazepine hypnotic
Temazepam with the birth control pill
Many women of reproductive age take a combined or progestogen-only oral contraceptive while also using a chronic medication such as Temazepam (Temazepam). The combination is generally fine at 7.5mg, 15mg, 22.5mg, 30mg, but a small number of medications can reduce contraceptive efficacy meaningfully and need either a backup method or a switch.
How Temazepam can affect contraceptive efficacy
Combined and progestogen-only contraceptives are metabolised through CYP3A4. Strong CYP3A4 inducers (some antiepileptics, rifampicin, St John's Wort) lower contraceptive plasma levels and reduce efficacy. Whether Temazepam acts on CYP3A4 determines whether Temazepam affects contraception. Most agents in Benzodiazepine hypnotic have no clinically meaningful effect on the pill at 7.5mg, 15mg, 22.5mg, 30mg.
Practical guidance
According to the prescribing information for Temazepam, women on hormonal contraception should review Temazepam with the prescribing pharmacist or doctor. Where an interaction is documented, additional barrier contraception or switching to a non-oral method (IUD, implant) for the duration of Temazepam therapy is the standard mitigation.
Frequently asked questions
Will Temazepam make my pill less effective? ▾
Most Benzodiazepine hypnotic medications at 7.5mg, 15mg, 22.5mg, 30mg do not affect oral contraceptive efficacy. The exceptions are CYP3A4-inducing drugs and a small number of others. The prescribing information for Temazepam states whether the interaction is meaningful.
Do I need a backup contraceptive on Temazepam? ▾
Backup contraception is needed only when there is a documented interaction between Temazepam and the contraceptive method. For most users at 7.5mg, 15mg, 22.5mg, 30mg, no backup is required. The pharmacist confirms whether Temazepam interacts with hormonal contraception.
Products containing Temazepam
More on Temazepam
- With alcoholTemazepam and alcohol — is it safe to drink?
- With foodShould Temazepam be taken with food?
- Side effectsTemazepam side effects: common, rare and warning signs
- Dosage guideTemazepam dosage guide: how much to take and when
- OnsetHow fast does Temazepam start working?
- DurationHow long does Temazepam last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.