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Short-acting SSRI (premature ejaculation)

Dapoxetine dosage guide: how much to take and when

Choosing the right dose of Dapoxetine (Dapoxetine) is the most important practical decision after starting therapy. Dapoxetine is supplied as tablet in 30mg, 60mg, and the right dose for a given person depends on the indication, age, comorbidities and tolerance to the active ingredient Dapoxetine.

Starting dose and titration

According to the prescribing information, most adults begin Dapoxetine at the lowest available strength of 30mg, 60mg and titrate up only if symptom control is insufficient and tolerability is good. Higher doses are reserved for selected cases. Older adults, people with renal or hepatic impairment, and those taking interacting medications should usually start at the lowest dose.

When to adjust

Dose adjustment is guided by symptom response and side effect burden, not by arbitrary schedules. Dapoxetine selectively blocks the serotonin transporter on the presynaptic neuron, increasing serotonin concentration in the synaptic cleft. If side effects are limiting at a given dose, going down a step is usually preferred over stopping abruptly. If the response is incomplete after several weeks, a higher dose can be tried under medical supervision.

Frequently asked questions

What is the standard starting dose of Dapoxetine?

Most adults start Dapoxetine at the lowest strength of 30mg, 60mg, with adjustment based on symptom response and tolerance. Older adults and those with reduced kidney or liver function generally start lower. The prescriber decides the exact starting dose for each person.

Can I take a higher dose of Dapoxetine if it isn't working?

Higher doses of Dapoxetine should only be used after consulting the prescriber. Doubling on your own is unsafe, especially with active ingredients in the Short-acting SSRI (premature ejaculation) class. The prescriber can confirm whether titration is appropriate or whether the medication needs to be changed.

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The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.