Selective serotonin reuptake inhibitor (SSRI)
Sertraline in the United States: prescription, brands, pricing
This page summarises the situation of Sertraline in the United States under FDA (Food and Drug Administration): prescription status, available brands and generics, pharmacy dispensing, and online options in USD. Sertraline belongs to the Selective serotonin reuptake inhibitor (SSRI) class.
- Regulator
- FDA (Food and Drug Administration)
- Currency
- USD
About Sertraline
Sertraline is approved for several psychiatric indications in adults: major depressive disorder, panic disorder with or without agoraphobia, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), social anxiety disorder… In the US, most prescription medications require a written or e-prescription from a licensed prescriber. A handful of formerly-prescription medications have moved to OTC after FDA review.
Mechanism and action
Sertraline selectively blocks the reuptake of serotonin (5-HT) by the presynaptic neuron, increasing the concentration of serotonin in the synaptic cleft.
Brands and generics in the United States
In the United States, Sertraline is typically dispensed as 2 internationally recognised brands along with their corresponding authorised generics. US pharmacies — both chain (CVS, Walgreens, Walmart) and independent — dispense Rx medications under state pharmacy board oversight. Pharmacist consultation is encouraged at pickup. Brand-to-generic substitution is decided by the pharmacist under local FDA (Food and Drug Administration) equivalence rules, and the price difference in USD is usually substantial.
Online and tele-prescribing access
Online prescription fulfilment in the US is well-regulated through state-licensed mail-order and tele-prescribing services. Importing prescription medication for personal use is restricted under federal law. For Sertraline specifically, the legal online options in the United States depend on its Rx-or-OTC classification under FDA (Food and Drug Administration).
Frequently asked questions
Is Sertraline available in the United States? ▾
Yes — Sertraline and its brands are available in the United States through pharmacies authorised by FDA (Food and Drug Administration), in various strengths depending on the commercial product. Authorised generics offer a lower-cost alternative with the same active substance.
Do I need a prescription for Sertraline in the United States? ▾
In the US, most prescription medications require a written or e-prescription from a licensed prescriber. A handful of formerly-prescription medications have moved to OTC after FDA review. The exact status of Sertraline (Rx or OTC) is determined by FDA (Food and Drug Administration); most active ingredients in the Selective serotonin reuptake inhibitor (SSRI) class require prescription, although there are exceptions by country and formulation.
How much does Sertraline cost in the United States? ▾
The price in USD depends on the manufacturer (brand vs authorised generic), the strength and the pack size. Generics are typically substantially cheaper than brands and serve as the economic reference for ongoing use.
Products with Sertraline in the United States
Sertraline in other countries
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.