Thiazide diuretic
Hydrochlorothiazide in the United States: prescription, brands, pricing
This page summarises the situation of Hydrochlorothiazide in the United States under FDA (Food and Drug Administration): prescription status, available brands and generics, pharmacy dispensing, and online options in USD. Hydrochlorothiazide belongs to the Thiazide diuretic class.
- Regulator
- FDA (Food and Drug Administration)
- Currency
- USD
About Hydrochlorothiazide
Hydrochlorothiazide is approved for hypertension (alone or in combination), oedema in heart failure, hepatic cirrhosis or nephrotic syndrome, and certain renal conditions. In the US, most prescription medications require a written or e-prescription from a licensed prescriber. A handful of formerly-prescription medications have moved to OTC after FDA review.
Mechanism and action
Hydrochlorothiazide blocks the sodium-chloride symporter in the distal convoluted tubule of the kidney, reducing sodium reabsorption and producing modest diuresis.
Brands and generics in the United States
In the United States, Hydrochlorothiazide is typically dispensed as one internationally recognised brand along with their corresponding authorised generics. US pharmacies — both chain (CVS, Walgreens, Walmart) and independent — dispense Rx medications under state pharmacy board oversight. Pharmacist consultation is encouraged at pickup. Brand-to-generic substitution is decided by the pharmacist under local FDA (Food and Drug Administration) equivalence rules, and the price difference in USD is usually substantial.
Online and tele-prescribing access
Online prescription fulfilment in the US is well-regulated through state-licensed mail-order and tele-prescribing services. Importing prescription medication for personal use is restricted under federal law. For Hydrochlorothiazide specifically, the legal online options in the United States depend on its Rx-or-OTC classification under FDA (Food and Drug Administration).
Frequently asked questions
Is Hydrochlorothiazide available in the United States? ▾
Yes — Hydrochlorothiazide and its brands are available in the United States through pharmacies authorised by FDA (Food and Drug Administration), in various strengths depending on the commercial product. Authorised generics offer a lower-cost alternative with the same active substance.
Do I need a prescription for Hydrochlorothiazide in the United States? ▾
In the US, most prescription medications require a written or e-prescription from a licensed prescriber. A handful of formerly-prescription medications have moved to OTC after FDA review. The exact status of Hydrochlorothiazide (Rx or OTC) is determined by FDA (Food and Drug Administration); most active ingredients in the Thiazide diuretic class require prescription, although there are exceptions by country and formulation.
How much does Hydrochlorothiazide cost in the United States? ▾
The price in USD depends on the manufacturer (brand vs authorised generic), the strength and the pack size. Generics are typically substantially cheaper than brands and serve as the economic reference for ongoing use.
Products with Hydrochlorothiazide in the United States
Hydrochlorothiazide in other countries
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.