Thiazide-like diuretic
Chlorthalidone in Japan: prescription, brands, pricing
This page summarises the situation of Chlorthalidone in Japan under PMDA (Pharmaceuticals and Medical Devices Agency): prescription status, available brands and generics, pharmacy dispensing, and online options in JPY. Chlorthalidone belongs to the Thiazide-like diuretic class.
- Regulator
- PMDA (Pharmaceuticals and Medical Devices Agency)
- Currency
- JPY
About Chlorthalidone
Chlorthalidone is approved for hypertension and oedema in heart failure, hepatic cirrhosis or nephrotic syndrome. Japan classifies medicines into prescription drugs (医療用医薬品) and OTC drugs (一般用医薬品), the latter further divided into pharmacist-only (第1類) and self-service classes. The Ministry of Health, Labour and Welfare (MHLW) sets the regulatory framework; PMDA reviews safety and efficacy.
Mechanism and action
Chlorthalidone blocks the sodium-chloride symporter in the distal convoluted tubule of the kidney, reducing sodium reabsorption and producing modest diuresis.
Brands and generics in Japan
In Japan, Chlorthalidone is typically dispensed as one internationally recognised brand along with their corresponding authorised generics. Japanese pharmacies (薬局) and drugstores (ドラッグストア) such as Matsumoto Kiyoshi and Welcia are widespread. Prescription dispensing pharmacies (調剤薬局) are usually located near hospitals and clinics; pharmacist counselling at dispensing is mandated by the Pharmaceutical Affairs Law. Brand-to-generic substitution is decided by the pharmacist under local PMDA (Pharmaceuticals and Medical Devices Agency) equivalence rules, and the price difference in JPY is usually substantial.
Online and tele-prescribing access
Japan permits online sale of most OTC medicines under the 2014 amendments to the Pharmaceutical Affairs Law, with class-based restrictions. Online prescription dispensing is allowed via licensed pharmacies after a face-to-face or telemedicine consultation; personal importation of prescription medication is restricted to limited quantities for personal use. For Chlorthalidone specifically, the legal online options in Japan depend on its Rx-or-OTC classification under PMDA (Pharmaceuticals and Medical Devices Agency).
Frequently asked questions
Is Chlorthalidone available in Japan? ▾
Yes — Chlorthalidone and its brands are available in Japan through pharmacies authorised by PMDA (Pharmaceuticals and Medical Devices Agency), in various strengths depending on the commercial product. Authorised generics offer a lower-cost alternative with the same active substance.
Do I need a prescription for Chlorthalidone in Japan? ▾
Japan classifies medicines into prescription drugs (医療用医薬品) and OTC drugs (一般用医薬品), the latter further divided into pharmacist-only (第1類) and self-service classes. The Ministry of Health, Labour and Welfare (MHLW) sets the regulatory framework; PMDA reviews safety and efficacy. The exact status of Chlorthalidone (Rx or OTC) is determined by PMDA (Pharmaceuticals and Medical Devices Agency); most active ingredients in the Thiazide-like diuretic class require prescription, although there are exceptions by country and formulation.
How much does Chlorthalidone cost in Japan? ▾
The price in JPY depends on the manufacturer (brand vs authorised generic), the strength and the pack size. Generics are typically substantially cheaper than brands and serve as the economic reference for ongoing use.
Products with Chlorthalidone in Japan
Chlorthalidone in other countries
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.