Potassium-sparing diuretic
Amiloride in Canada: prescription, brands, pricing
This page summarises the situation of Amiloride in Canada under Health Canada: prescription status, available brands and generics, pharmacy dispensing, and online options in CAD. Amiloride belongs to the Potassium-sparing diuretic class.
- Regulator
- Health Canada
- Currency
- CAD
About Amiloride
Amiloride is approved for hypertension (typically in combination with thiazides), oedema in heart failure or hepatic cirrhosis (in combination), and primary hyperaldosteronism (Liddle syndrome and pseudohyperaldosteronism). Canada classifies medications as Schedule I (prescription), II (pharmacist-only OTC), III (open OTC) or unscheduled, with provincial variation. Provincial drug plans cover prescription costs at varying rates.
Mechanism and action
Amiloride blocks the epithelial sodium channel (ENaC) in the distal convoluted tubule and collecting duct of the kidney, reducing sodium reabsorption and indirectly decreasing potassium and hydrogen ion excretion.
Brands and generics in Canada
In Canada, Amiloride is typically dispensed as one internationally recognised brand along with their corresponding authorised generics. Canadian pharmacies (Shoppers Drug Mart, Rexall, London Drugs and many independents) are licensed provincially, and pharmacists in several provinces can prescribe for minor ailments. Brand-to-generic substitution is decided by the pharmacist under local Health Canada equivalence rules, and the price difference in CAD is usually substantial.
Online and tele-prescribing access
Online pharmacy is regulated provincially in Canada; cross-border imports are restricted. Tele-prescribing platforms have expanded prescription access since 2020. For Amiloride specifically, the legal online options in Canada depend on its Rx-or-OTC classification under Health Canada.
Frequently asked questions
Is Amiloride available in Canada? ▾
Yes — Amiloride and its brands are available in Canada through pharmacies authorised by Health Canada, in various strengths depending on the commercial product. Authorised generics offer a lower-cost alternative with the same active substance.
Do I need a prescription for Amiloride in Canada? ▾
Canada classifies medications as Schedule I (prescription), II (pharmacist-only OTC), III (open OTC) or unscheduled, with provincial variation. Provincial drug plans cover prescription costs at varying rates. The exact status of Amiloride (Rx or OTC) is determined by Health Canada; most active ingredients in the Potassium-sparing diuretic class require prescription, although there are exceptions by country and formulation.
How much does Amiloride cost in Canada? ▾
The price in CAD depends on the manufacturer (brand vs authorised generic), the strength and the pack size. Generics are typically substantially cheaper than brands and serve as the economic reference for ongoing use.
Products with Amiloride in Canada
Amiloride in other countries
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.