Viagra Professional with antibiotics: interactions and safety
Antibiotic courses are common, short-term and often combined with chronic medications such as Viagra Professional (Sildenafil Citrate). Most antibiotics do not interfere meaningfully with Sildenafil Citrate at 100mg, but a few classes do, and a small number of combinations are best avoided.
Common antibiotic interactions
Macrolides (clarithromycin, erythromycin) and certain antifungals can inhibit hepatic metabolism (CYP3A4) and raise plasma levels of many medications including some Erectile Dysfunction (ED) agents. Rifampicin has the opposite effect, accelerating metabolism. Most penicillins, cephalosporins, fluoroquinolones and tetracyclines have no clinically meaningful interaction with Sildenafil Citrate at 100mg.
Practical guidance
According to the prescribing information for Sildenafil Citrate, an antibiotic course should be reviewed by the prescriber or pharmacist for known interactions before Viagra Professional is co-administered. Adjusted 100mg dosing or temporary substitution is sometimes preferred for the duration of the antibiotic course.
Frequently asked questions
Can I take Viagra Professional during an antibiotic course? ▾
For most common antibiotics, yes. A few classes — notably macrolides and azole antifungals — alter how Sildenafil Citrate is metabolised and may need a temporary 100mg adjustment. The prescribing pharmacist should review any new antibiotic against the existing Viagra Professional regimen.
Will antibiotics make Viagra Professional stop working? ▾
Most antibiotics do not affect Viagra Professional efficacy. Rifampicin and a few others can lower Sildenafil Citrate levels and reduce effect; in those cases the prescriber may adjust the dose during and shortly after the antibiotic course.
More on Viagra Professional
- With alcoholViagra Professional and alcohol — is it safe to drink?
- With foodShould Viagra Professional be taken with food?
- Side effectsViagra Professional side effects: common, rare and warning signs
- Dosage guideViagra Professional dosage guide: how much to take and when
- OnsetHow fast does Viagra Professional start working?
- DurationHow long does Viagra Professional last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.