Viagra Professional with kidney impairment: dosing and safety
Kidney function affects how the body clears Viagra Professional (Sildenafil Citrate) and many of its metabolites. For people with chronic kidney disease, dialysis, or even mild renal impairment from age or comorbidities, the standard 100mg dose may need adjustment. This page summarises the practical principles for Viagra Professional in renal impairment.
Why renal function matters for Viagra Professional
A meaningful fraction of Sildenafil Citrate or its active metabolites is cleared by the kidneys for many medications. Reduced eGFR slows clearance, raises plasma concentrations and prolongs effect. Sildenafil citrate inhibits PDE5, allowing the cyclic GMP produced during sexual arousal to accumulate in penile tissue, which relaxes the smooth muscle of the penile arteries and increases blood infl… The prescribing information for Sildenafil Citrate usually specifies dose adjustments by eGFR threshold (e.g. 30–60 vs <30 mL/min/1.73m²).
Practical guidance
According to the prescribing information, baseline kidney function should be checked before starting Viagra Professional and periodically during treatment. People on dialysis need specialist input on dose timing relative to dialysis. Acute kidney injury — from dehydration, infection or other medications — can shift Viagra Professional effects unpredictably and may warrant a temporary hold at 100mg.
Frequently asked questions
Is Viagra Professional safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Viagra Professional at adjusted lower 100mg doses with monitoring. Severe impairment (eGFR <30) often requires substantial reduction or alternative therapy. The prescriber decides based on lab results and the indication.
Do I need lab tests on Viagra Professional if I have kidney disease? ▾
Yes — periodic eGFR and electrolyte monitoring is the standard practice for Viagra Professional in chronic kidney disease. Frequency depends on the severity of impairment and on Sildenafil Citrate-specific risks. The prescriber sets the schedule.
More on Viagra Professional
- With alcoholViagra Professional and alcohol — is it safe to drink?
- With foodShould Viagra Professional be taken with food?
- Side effectsViagra Professional side effects: common, rare and warning signs
- Dosage guideViagra Professional dosage guide: how much to take and when
- OnsetHow fast does Viagra Professional start working?
- DurationHow long does Viagra Professional last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.