Tamiflu 45mg

Forms and dosages

Tamiflu is administered orally with or without food, ideally with food to reduce gastrointestinal side effects. According to the prescribing information, the usual adult dose for treatment is 75mg twice daily for 5 days, and for post-exposure prophylaxis is 75mg once daily for 7-10 days. Paediatric dosing is weight-based using the oral suspension. Substantial dose reduction is required in renal impairment.

Indications

Tamiflu is approved in adults and children for the treatment of acute uncomplicated influenza A and B when started within 48 hours of symptom onset, and for post-exposure prophylaxis of influenza A and B in patients aged 1 year and older. According to international guidelines, treatment is recommended for patients at high risk of complications, those requiring hospitalisation and severe progressive disease. Routine treatment of low-risk patients with mild influenza is more controversial.