Femalegra with antibiotics: interactions and safety
Antibiotic courses are common, short-term and often combined with chronic medications such as Femalegra (Sildenafil Citrate). Most antibiotics do not interfere meaningfully with Sildenafil Citrate at 100mg, but a few classes do, and a small number of combinations are best avoided.
Common antibiotic interactions
Macrolides (clarithromycin, erythromycin) and certain antifungals can inhibit hepatic metabolism (CYP3A4) and raise plasma levels of many medications including some Women's Sexual Health agents. Rifampicin has the opposite effect, accelerating metabolism. Most penicillins, cephalosporins, fluoroquinolones and tetracyclines have no clinically meaningful interaction with Sildenafil Citrate at 100mg.
Practical guidance
According to the prescribing information for Sildenafil Citrate, an antibiotic course should be reviewed by the prescriber or pharmacist for known interactions before Femalegra is co-administered. Adjusted 100mg dosing or temporary substitution is sometimes preferred for the duration of the antibiotic course.
Frequently asked questions
Can I take Femalegra during an antibiotic course? ▾
For most common antibiotics, yes. A few classes — notably macrolides and azole antifungals — alter how Sildenafil Citrate is metabolised and may need a temporary 100mg adjustment. The prescribing pharmacist should review any new antibiotic against the existing Femalegra regimen.
Will antibiotics make Femalegra stop working? ▾
Most antibiotics do not affect Femalegra efficacy. Rifampicin and a few others can lower Sildenafil Citrate levels and reduce effect; in those cases the prescriber may adjust the dose during and shortly after the antibiotic course.
More on Femalegra
- With alcoholFemalegra and alcohol — is it safe to drink?
- With foodShould Femalegra be taken with food?
- Side effectsFemalegra side effects: common, rare and warning signs
- Dosage guideFemalegra dosage guide: how much to take and when
- OnsetHow fast does Femalegra start working?
- DurationHow long does Femalegra last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.