Who should not take Evista
A contraindication is a condition under which Evista (Raloxifene) should not be taken because the risk outweighs the benefit. Evista has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 60mg dosing range.
Absolute contraindications
According to the prescribing information for Raloxifene, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Evista can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Raloxifene binds estrogen receptors and produces tissue-selective effects: estrogen-agonist activity in bone (preserving bone mineral density) and on lipid metabolism (lowering LDL cholesterol), while…
Frequently asked questions
Can someone with heart disease take Evista? ▾
Some forms of heart disease are absolute contraindications for Evista, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Evista use under specialist supervision. The prescribing information for Raloxifene should be reviewed.
Is Evista safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Evista at adjusted lower 60mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
More on Evista
- With alcoholEvista and alcohol — is it safe to drink?
- With foodShould Evista be taken with food?
- Side effectsEvista side effects: common, rare and warning signs
- Dosage guideEvista dosage guide: how much to take and when
- OnsetHow fast does Evista start working?
- DurationHow long does Evista last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.